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A Randomized, Open-Label, Active-Controlled, Multi-Center, Phase III Clinical Study of Anti-PD-1 Antibody SHR-1210 vs. Investigator's Choice of Chemotherapy in Subjects With Locally Advanced or Metastatic Esophageal Cancer

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Trial Profile

A Randomized, Open-Label, Active-Controlled, Multi-Center, Phase III Clinical Study of Anti-PD-1 Antibody SHR-1210 vs. Investigator's Choice of Chemotherapy in Subjects With Locally Advanced or Metastatic Esophageal Cancer

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 24 Jan 2024

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At a glance

  • Drugs Camrelizumab (Primary) ; Docetaxel; Irinotecan
  • Indications Carcinoma; Oesophageal cancer; Squamous cell cancer
  • Focus Therapeutic Use
  • Acronyms ESCORT
  • Sponsors Jiangsu Hengrui Medicine Co.

    • Most Recent Events

    • 01 Dec 2021 Results assessing PD-L1 Expression on circulating tumor cells for predicting clinical outcomes by using data from six clinical trials including this study published in the Oncologist
    • 15 Nov 2021 Results (N=1683) of meta-analysis and systematic review evaluating the efficacy and safety of PD-1 inhibitors monotherapy versus chemotherapy in second-line treatment of AEC published in the Clinical Therapeutics
    • 13 May 2020 Primary endpoint (Overall Survival (OS)) has been met, as per Results published in the Lancet Oncology

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