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Phase Ib Trial of CAR-T Hepatic Artery Infusions Followed by Selective Internal Radiation Therapy (SIRT) With Yttrium-90 Sir-Spheres for CEA-Expressing Liver Metastases

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Phase Ib Trial of CAR-T Hepatic Artery Infusions Followed by Selective Internal Radiation Therapy (SIRT) With Yttrium-90 Sir-Spheres for CEA-Expressing Liver Metastases

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 05 Nov 2021

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At a glance

  • Drugs Anti CEA CAR T cell therapy Sorrento Therapeutics (Primary) ; Interleukin-2; Yttrium-90
  • Indications Adenocarcinoma; Liver metastases
  • Focus Adverse reactions
  • Acronyms HITM-SIR

    • Most Recent Events

    • 25 Mar 2019 Status changed from active, no longer recruiting to completed.
    • 15 Jun 2018 Planned End Date changed from 1 Sep 2017 to 1 Jan 2019.
    • 28 Mar 2018 According to a Sorrento Therapeutics media release, the Company expects to complete this trial in 2H 2018.

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