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A Phase 1, Randomized, Open-label, Crossover Study to Evaluate the Effect of the Organic Anion Transporter Inhibitor Probenecid on the Pharmacokinetics of JNJ-64041575 in Healthy Adult Subjects

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Trial Profile

A Phase 1, Randomized, Open-label, Crossover Study to Evaluate the Effect of the Organic Anion Transporter Inhibitor Probenecid on the Pharmacokinetics of JNJ-64041575 in Healthy Adult Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 14 Apr 2021

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At a glance

  • Drugs Lumicitabine (Primary) ; Probenecid
  • Indications Metapneumovirus infections; Parainfluenza virus infections; Respiratory syncytial virus infections
  • Focus Pharmacokinetics
  • Sponsors Janssen-Cilag

    • Most Recent Events

    • 10 Apr 2021 Results of an analysis using urine and plasma samples from this study assessing mechanisms and transporters involved in renal excretion of endogenous biomarkers published in the Clinical Pharmacokinetics
    • 24 Jul 2017 Status changed from recruiting to completed.
    • 12 May 2017 Planned End Date changed from 6 Dec 2017 to 12 Jun 2017.

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