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Phase I/II Trial of Pembrolizumab in Combination With Binimetinib in Unresectable Locally Advanced or Metastatic Triple Negative Breast Cancer

Trial Profile

Phase I/II Trial of Pembrolizumab in Combination With Binimetinib in Unresectable Locally Advanced or Metastatic Triple Negative Breast Cancer

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 22 Aug 2024

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At a glance

  • Drugs Binimetinib (Primary) ; Pembrolizumab (Primary)
  • Indications Adenocarcinoma; Advanced breast cancer; HER2 negative breast cancer; Liver metastases; Male breast cancer; Triple negative breast cancer
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 01 Aug 2023 Status changed from active, no longer recruiting to completed.
  • 19 Apr 2023 Results assessing potential biomarkers in peripheral blood to predict response presented at the 114th Annual Meeting of the American Association for Cancer Research
  • 12 Jan 2023 Planned primary completion date changed from 15 Jun 2023 to 15 Jul 2023.

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