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Phase 0/I Study of AMG 232 (KRT 232) Concentrations in Brain Tissue in Patients With Recurrent Glioblastoma and of AMG 232 (KRT 232) in Combination With Radiation in Patients With Newly Diagnosed Glioblastoma and Unmethylated MGMT Promoters

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Trial Profile

Phase 0/I Study of AMG 232 (KRT 232) Concentrations in Brain Tissue in Patients With Recurrent Glioblastoma and of AMG 232 (KRT 232) in Combination With Radiation in Patients With Newly Diagnosed Glioblastoma and Unmethylated MGMT Promoters

Status: Suspended
Phase of Trial: Phase I

Latest Information Update: 27 Aug 2024

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At a glance

  • Drugs Navtemadlin (Primary)
  • Indications Glioblastoma; Gliosarcoma
  • Focus Adverse reactions; Pharmacokinetics
  • Most Recent Events

    • 23 Aug 2024 Status changed from recruiting to suspended.
    • 02 Jan 2024 Planned End Date changed from 31 Dec 2023 to 31 Dec 2024.
    • 02 Jan 2024 Planned primary completion date changed from 31 Dec 2023 to 31 Dec 2024.

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