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A Phase II Trial of the Mitogen Activated Protein Kinase Kinase (MEK1/2) Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Patients With Neurofibromatosis Type 1 (NF1) Mutated Gastrointestinal Stromal Tumors (GIST)

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Trial Profile

A Phase II Trial of the Mitogen Activated Protein Kinase Kinase (MEK1/2) Inhibitor Selumetinib (AZD6244 Hydrogen Sulfate) in Patients With Neurofibromatosis Type 1 (NF1) Mutated Gastrointestinal Stromal Tumors (GIST)

Status: Withdrawn prior to enrolment
Phase of Trial: Phase II

Latest Information Update: 05 Nov 2021

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At a glance

  • Drugs Selumetinib (Primary)
  • Indications Gastrointestinal stromal tumours; Neurofibroma; Neurofibromatosis 1
  • Focus Therapeutic Use
  • Most Recent Events

    • 03 Apr 2019 Planned initiation date changed from 2 Apr 2018 to 7 Apr 2017.
    • 29 Mar 2019 Planned End Date changed from 1 Feb 2023 to 27 Mar 2019.
    • 29 Mar 2019 Planned primary completion date changed from 1 Feb 2022 to 27 Mar 2019.

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