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A Phase 1, Open-Label Study to Characterize the Pharmacokinetics and Safety of a Single Oral Dose of GBT440 in Subjects With Hepatic Impairment

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Trial Profile

A Phase 1, Open-Label Study to Characterize the Pharmacokinetics and Safety of a Single Oral Dose of GBT440 in Subjects With Hepatic Impairment

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 19 Jul 2023

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At a glance

  • Drugs Voxelotor (Primary)
  • Indications Liver disorders
  • Focus Pharmacokinetics
  • Sponsors Global Blood Therapeutics; Pfizer

    • Most Recent Events

    • 20 Oct 2020 Results of two studies ( NCT03161015 and NCT03114540) assessing pharmacokinetics of Voxelotor published in the Journal of Clinical Pharmacology
    • 17 Apr 2018 Status changed from active, no longer recruiting to completed.
    • 20 Feb 2018 Planned End Date changed from 1 Nov 2017 to 8 Mar 2018.

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