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DAPHNE Study: Real-Life Observational Study to Evaluate the Impact of the CYP3A4/5/7 and P-gp Pharmacogenetics and Phenotypic Activity on the Pharmacokinetic Profile of the Direct Oral Anticoagulants Rivaroxaban and Apixaban in Hospitalised Patients

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Trial Profile

DAPHNE Study: Real-Life Observational Study to Evaluate the Impact of the CYP3A4/5/7 and P-gp Pharmacogenetics and Phenotypic Activity on the Pharmacokinetic Profile of the Direct Oral Anticoagulants Rivaroxaban and Apixaban in Hospitalised Patients

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 07 Oct 2021

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At a glance

  • Drugs Apixaban (Primary) ; Rivaroxaban (Primary)
  • Indications Deep vein thrombosis; Pulmonary embolism
  • Focus Pharmacokinetics
  • Acronyms DAPHNE

    • Most Recent Events

    • 29 Sep 2021 Status changed from recruiting to completed.
    • 23 Mar 2020 Planned End Date changed from 1 Apr 2019 to 1 Oct 2020.
    • 23 Mar 2020 Planned primary completion date changed from 1 Apr 2019 to 1 Apr 2020.

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