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Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable high grade gliomas patients

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Trial Profile

Phase I/IIa study of concomitant radiotherapy with olaparib and temozolomide in unresectable high grade gliomas patients

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 06 May 2024

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At a glance

  • Drugs Olaparib (Primary) ; Temozolomide
  • Indications Glioblastoma; Glioma
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms OLA-TMZ-RTE-01
  • Most Recent Events

    • 26 Apr 2024 Planned End Date changed from 4 Oct 2024 to 4 Mar 2025.
    • 26 Apr 2024 Planned primary completion date changed from 4 Apr 2024 to 13 Sep 2024.
    • 06 Jun 2023 Results (n=30) of phase 1 step assessing safety and efficacy of olaparib combined with radiotherapy plus temozolomide in high grade glioma patients, presented at the 59th Annual Meeting of the American Society of Clinical Oncology.

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