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A Phase 1, Multi-Center, Open-Label, Dose-Escalation, Safety, Pharmacokinetic, and Pharmacodynamic Study of Minnelide Capsules Given Alone or in Combination With Protein-Bound Paclitaxel in Patients With Advanced Solid Tumors

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Trial Profile

A Phase 1, Multi-Center, Open-Label, Dose-Escalation, Safety, Pharmacokinetic, and Pharmacodynamic Study of Minnelide Capsules Given Alone or in Combination With Protein-Bound Paclitaxel in Patients With Advanced Solid Tumors

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 20 Oct 2023

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At a glance

  • Drugs Minnelide (Primary) ; Paclitaxel
  • Indications Advanced breast cancer; Gastric cancer; Gastrointestinal cancer; Pancreatic cancer; Solid tumours
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms Minnelide 101
  • Sponsors Minneamrita Therapeutics

    • Most Recent Events

    • 17 Oct 2023 Planned End Date changed from 1 Dec 2022 to 1 Dec 2024.
    • 17 Oct 2023 Planned primary completion date changed from 1 Aug 2022 to 1 Jun 2024.
    • 04 Apr 2022 Planned End Date changed from 1 Dec 2021 to 1 Dec 2022.

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