Effects of Concomitant Administration of BMS-986195 on the Single-dose Pharmacokinetics of Methotrexate and Probe Substrates for Cytochrome P450 1A2, 2C8, 2C9, 2C19, 3A4, Organic Anion Transporter Polypeptide 1B1 and P-glycoprotein in Healthy Participants

Trial Profile

Effects of Concomitant Administration of BMS-986195 on the Single-dose Pharmacokinetics of Methotrexate and Probe Substrates for Cytochrome P450 1A2, 2C8, 2C9, 2C19, 3A4, Organic Anion Transporter Polypeptide 1B1 and P-glycoprotein in Healthy Participants

Completed
Phase of Trial: Phase I

Latest Information Update: 20 Dec 2017

At a glance

  • Drugs BMS 986195 (Primary) ; Folinic acid; Methotrexate
  • Indications Rheumatoid arthritis
  • Focus Pharmacokinetics
  • Sponsors Bristol-Myers Squibb
  • Most Recent Events

    • 13 Dec 2017 Status changed from not yet recruiting to completed.
    • 02 May 2017 New trial record
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