Trial Profile

Phase I/II Study of the Selective PI3K-Beta Inhibitor GSK2636771 in Combination With Pembrolizumab in Patients With Metastatic Melanoma and PTEN Loss

Status: Active, no longer recruiting

Phase of Trial: Phase I/II

Latest Information Update: 09 Jan 2026

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At a glance

Drugs GSK 2636771 (Primary) ; Pembrolizumab (Primary)
Indications Advanced breast cancer; Cancer; Endometrial cancer; Malignant melanoma; Prostate cancer; Triple negative breast cancer
Focus Adverse reactions; Therapeutic Use

Most Recent Events

15 Dec 2025 Planned End Date changed from 31 Dec 2025 to 31 Dec 2027.
15 Dec 2025 Planned primary completion date changed from 31 Dec 2025 to 31 Dec 2027.
31 Jul 2023 Planned End Date changed from 31 Dec 2023 to 31 Dec 2025.

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