Trial Profile

A prospective, multicenter, phase-II trial of ibrutinib plus venetoclax in patients with creatinine clearance ≥ 30 ml/min who have relapsed or refractory chronic lymphocytic leukemia (RR-CLL) with or without TP53 aberrations

Status: Completed

Phase of Trial: Phase II

Latest Information Update: 18 Aug 2026

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At a glance

13 Apr 2026 This trial has been completed in Finland, Sweden, Belgium and Norway.
15 Jun 2023 Results identifying functional biomarkers at baseline that predict MRD status at month 15 in the patients enrolled in this study, presented at the 28th Congress of the European Haematology Association
15 Jun 2023 Results analyzing the relation between LN-mediated signaling, and the potential to induce venetoclax resistance presented at the 28th Congress of the European Haematology Association

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