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A PHASE 2, MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF CC-220 IN SUBJECTS WITH ACTIVE SYSTEMIC LUPUS ERYTHEMATOSUS

Trial Profile

A PHASE 2, MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF CC-220 IN SUBJECTS WITH ACTIVE SYSTEMIC LUPUS ERYTHEMATOSUS

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 02 Jan 2024

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At a glance

  • Drugs Iberdomide (Primary)
  • Indications Systemic lupus erythematosus
  • Focus Therapeutic Use
  • Sponsors Celgene Corporation
  • Most Recent Events

    • 15 Nov 2023 Results (n=276) assessing to identify the profile of gene expression abnormalities in systemic lupus erythematosus patients responsive to iberdomide and the impact of the agent on gene expression abnormalities, presented at the ACR Convergence 2023.
    • 03 Jun 2023 Blood samples from 276 female SLE patients from this study were used to identify subsets of SLE patients responsive to iberdomide more effectively by analyzing baseline gene expression profiles, presented at the 24th Annual Congress of the European League Against Rheumatism.
    • 27 Apr 2022 Results assessing biological impact of iberdomide in patients with active systemic lupus erythematosus, published in the Annals of the Rheumatic Diseases.
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