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Phase 1 Study of Pazopanib in Combination With Irinotecan and Temozolomide (PAZIT) for Children and Young Adults With Relapsed or Refractory Sarcoma

Trial Profile

Phase 1 Study of Pazopanib in Combination With Irinotecan and Temozolomide (PAZIT) for Children and Young Adults With Relapsed or Refractory Sarcoma

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 26 Jul 2019

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At a glance

  • Drugs Irinotecan (Primary) ; Irinotecan (Primary) ; Pazopanib (Primary) ; Temozolomide (Primary)
  • Indications Ewing's sarcoma; Osteosarcoma; Primitive neuroectodermal tumours; Rhabdomyosarcoma; Sarcoma; Soft tissue sarcoma
  • Focus Adverse reactions
  • Acronyms PAZIT
  • Most Recent Events

    • 24 Jun 2019 Planned number of patients changed from 18 to 32.
    • 06 Mar 2019 Planned End Date changed from 30 Nov 2019 to 30 Jun 2021.
    • 06 Mar 2019 Planned primary completion date changed from 30 Nov 2018 to 30 Jun 2020.
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