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An Open-label, Phase I Dose Escalation Trial of Methionine Aminopeptidase 2 Inhibitor M8891 in Subjects With Advanced Solid Tumors

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Trial Profile

An Open-label, Phase I Dose Escalation Trial of Methionine Aminopeptidase 2 Inhibitor M8891 in Subjects With Advanced Solid Tumors

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 14 Mar 2022

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At a glance

  • Drugs M 8891 (Primary)
  • Indications Renal cell carcinoma; Solid tumours
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Sponsors EMD Serono Research & Development Institute
  • Most Recent Events

    • 29 Oct 2020 Status changed from recruiting to active, no longer recruiting.
    • 21 Sep 2020 Preliminary results (n=24) of dose escalation part of this trial presented at the 45th European Society for Medical Oncology Congress
    • 15 Jul 2020 Planned number of patients changed from 27 to 97.

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