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A proof of concept clinical trial assessing the safety of the coordinated undermining of survival paths by 9 repurposed drugs combined with metronomic temozolomide (CUSP9v3 Treatment Protocol) for recurrent glioblastoma

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Trial Profile

A proof of concept clinical trial assessing the safety of the coordinated undermining of survival paths by 9 repurposed drugs combined with metronomic temozolomide (CUSP9v3 Treatment Protocol) for recurrent glioblastoma

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 10 Oct 2021

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At a glance

  • Drugs Aprepitant (Primary) ; Auranofin (Primary) ; Captopril (Primary) ; Celecoxib (Primary) ; Disulfiram (Primary) ; Itraconazole (Primary) ; Minocycline (Primary) ; Ritonavir (Primary) ; Sertraline (Primary) ; Temozolomide (Primary)
  • Indications Glioblastoma
  • Focus Adverse reactions; Proof of concept; Therapeutic Use
  • Most Recent Events

    • 24 Dec 2020 Status changed from recruiting to completed.
    • 09 May 2017 New trial record

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