Phase II Study of the Sequential Combination of Low-Intensity Chemotherapy and Ponatinib Followed by Blinatumomab and Ponatinib in Patients With Philadelphia Chromosome (Ph)-Positive and/or BCR-ABL Positive Acute Lymphoblastic Leukemia (ALL)

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 10 Feb 2025

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At a glance

Drugs Blinatumomab (Primary) ; Ponatinib (Primary) ; Rituximab (Primary) ; Cyclophosphamide; Cytarabine; Cytarabine; Filgrastim; Methotrexate; Methotrexate; Pegfilgrastim; Prednisone; Vincristine
Indications Chronic myeloid leukaemia; Precursor cell lymphoblastic leukaemia-lymphoma
Focus Therapeutic Use

Most Recent Events

07 Feb 2025 Planned End Date changed from 28 Feb 2025 to 28 Feb 2027.
07 Feb 2025 Planned primary completion date changed from 28 Feb 2025 to 28 Feb 2027.
11 Jan 2024 Planned End Date changed from 8 Feb 2024 to 28 Feb 2025.

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