Trial Profile

Palbociclib After CDK and Endocrine Therapy (PACE): A Randomized Phase II Study of Fulvestrant, Palbociclib, and Avelumab for Endocrine Pre-treated ER+/HER2- Metastatic Breast Cancer

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 16 Sep 2026

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At a glance

Drugs Avelumab (Primary) ; Fulvestrant (Primary) ; Palbociclib (Primary)
Indications Advanced breast cancer; HER2 negative breast cancer; Male breast cancer
Focus Therapeutic Use
Acronyms PACE

Most Recent Events

11 Sep 2026 Planned End Date changed from 30 Jun 2026 to 30 Dec 2026.
27 Aug 2025 Planned End Date changed from 30 Jun 2025 to 30 Jun 2026.
06 Mar 2025 Planned End Date changed from 31 Dec 2024 to 30 Jun 2025.

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