Palbociclib After CDK and Endocrine Therapy (PACE): A Randomized Phase II Study of Fulvestrant, Palbociclib, and Avelumab for Endocrine Pre-treated ER+/HER2- Metastatic Breast Cancer
Latest Information Update: 10 Mar 2025
At a glance
- Drugs Avelumab (Primary) ; Fulvestrant (Primary) ; Palbociclib (Primary)
- Indications Advanced breast cancer; HER2 negative breast cancer; Male breast cancer
- Focus Therapeutic Use
- Acronyms PACE
- 06 Mar 2025 Planned End Date changed from 31 Dec 2024 to 30 Jun 2025.
- 06 Jun 2023 Results of biomarker analysis of palbociclib in combination with fulvestrant after progression on any CDK4/6 inhibitor in metastatic breast cancer, presented at the 59th Annual Meeting of the American Society of Clinical Oncology.
- 19 Sep 2022 Planned primary completion date changed from 31 Aug 2022 to 31 Dec 2022.