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FIGHT: A Phase 2 Randomized, Double-Blind, Controlled Study Evaluating Bemarituzumab (FPA144) and Modified FOLFOX6 in Patients With Previously Untreated Advanced Gastric and Gastroesophageal Junction Cancer: Phase 2 Preceded by Dose-Finding in Phase 1

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FIGHT: A Phase 2 Randomized, Double-Blind, Controlled Study Evaluating Bemarituzumab (FPA144) and Modified FOLFOX6 in Patients With Previously Untreated Advanced Gastric and Gastroesophageal Junction Cancer: Phase 2 Preceded by Dose-Finding in Phase 1

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 01 Mar 2024

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At a glance

  • Drugs Bemarituzumab (Primary) ; Fluorouracil; Folinic acid; Oxaliplatin
  • Indications Adenocarcinoma; Gastric cancer; Oesophageal cancer
  • Focus Therapeutic Use
  • Acronyms FIGHT
  • Sponsors Five Prime Therapeutics

    • Most Recent Events

    • 13 Oct 2022 Results published in the Lancet Oncology
    • 14 Jun 2022 Status changed from active, no longer recruiting to completed.
    • 08 Jun 2021 Results assessing updated analyses of patient subgroups, additional data on ocular adverse events, and the median OS result for the bema+mFOLFOX6 combination, presented at the 57th Annual Meeting of the American Society of Clinical Oncology

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