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A Single Arm Phase I-II Multicenter Trial With Avelumab Plus Autologous Dendritic Cell Vaccine to Determine Safety and Preliminary Efficacy of the Combination in Pre-treated Mismatch Repair-proficient (MSS) Metastatic Colorectal Cancer Patients.

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Trial Profile

A Single Arm Phase I-II Multicenter Trial With Avelumab Plus Autologous Dendritic Cell Vaccine to Determine Safety and Preliminary Efficacy of the Combination in Pre-treated Mismatch Repair-proficient (MSS) Metastatic Colorectal Cancer Patients.

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 08 Apr 2023

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At a glance

  • Drugs Avelumab (Primary) ; Dendritic cell vaccines
  • Indications Adenocarcinoma; Colorectal cancer
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms AVEVAC

    • Most Recent Events

    • 01 Apr 2023 Results assessing the safety, pharmacodynamics and anti-tumor effects of Avelumab plus autologous dendritic cells vaccine in heavily pre-treated mismatch repair-deficient/microsatellite instability high metastatic colorectal cancer patients, published in the Cancer Immunology Immunotherapy.
    • 21 Sep 2021 Results presented at the 46th European Society for Medical Oncology Congress
    • 05 Oct 2020 Status changed from active, no longer recruiting to completed.

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