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A phase I/II multiple ascending dose open-label safety and efficacy study of the Notch Inhibitor LY3056480 in patients with mild to moderate sensorineural hearing loss
A phase I/II multiple ascending dose open-label safety and efficacy study of the Notch Inhibitor LY3056480 in patients with mild to moderate sensorineural hearing loss
Status:Active, no longer recruiting
Phase of Trial:
Phase I/II
Latest Information Update:08 Jan 2020
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Focus
Adverse reactions; First in man; Therapeutic Use
Acronyms
REGAIN
Sponsors
Audion Therapeutics
Most Recent Events
05 Feb 2019
According to the Audion Therapeutics media release, recruitment for phase II part of the study started in January 2019 and company plans to enroll 40 adult patients in UK, Germany and Greece. Efficacy parameters for this phase are pure tone hearing levels and speech in noise performance.
05 Feb 2019
Positive phase I results presented in the Audion Therapeutics media release.
23 May 2017
New trial record
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