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A Two-part, Randomized, Placebo-controlled, Patient and Investigator Blinded, Study Investigating the Safety, Tolerability and Preliminary Efficacy of Intra-articular LNA043 Injections in Regenerating the Articular Cartilage of the Knee in Patients With Articular Cartilage Lesions (Part A) and in Patients With Knee Osteoarthritis (Part B)

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A Two-part, Randomized, Placebo-controlled, Patient and Investigator Blinded, Study Investigating the Safety, Tolerability and Preliminary Efficacy of Intra-articular LNA043 Injections in Regenerating the Articular Cartilage of the Knee in Patients With Articular Cartilage Lesions (Part A) and in Patients With Knee Osteoarthritis (Part B)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 19 Feb 2024

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At a glance

  • Drugs LNA 043 (Primary)
  • Indications Cartilage disorders; Osteoarthritis
  • Focus Adverse reactions; Proof of concept; Therapeutic Use
  • Sponsors Novartis Pharma A.G.; Novartis Pharmaceuticals

    • Most Recent Events

    • 08 Dec 2022 This trial has been completed in Czech Republic (global end date 06/09/2022), according to European Clinical Trials Database record.
    • 04 Oct 2022 Status changed from active, no longer recruiting to completed.
    • 15 Sep 2021 Status changed from recruiting to active, no longer recruiting.

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