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Evaluation of the Combination of Selumetinib and Olaparib in Endometrial, Ovarian and Other Solid Tumors with Ras Pathway Alterations, and Ovarian Tumors with PARP Resistance

Trial Profile

Evaluation of the Combination of Selumetinib and Olaparib in Endometrial, Ovarian and Other Solid Tumors with Ras Pathway Alterations, and Ovarian Tumors with PARP Resistance

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 07 May 2025

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At a glance

  • Drugs Olaparib (Primary) ; Selumetinib (Primary)
  • Indications Endometrial cancer; Ovarian cancer; Solid tumours
  • Focus Adverse reactions

Most Recent Events

  • 31 Aug 2022 Status changed from recruiting to active, no longer recruiting.
  • 29 Dec 2021 Planned End Date changed from 1 Aug 2026 to 30 Aug 2026.
  • 29 Dec 2021 Planned primary completion date changed from 1 Aug 2026 to 30 Aug 2026.

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