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A Phase 2 Interventional, Multicenter, Randomized Open Label Study to Determine the Effective and Tolerable Dose of KAF156 and Lumefantrine Solid Dispersion Formulation in Combination, Given Once Daily for 1, 2 and 3-days to Adults and Children With Uncomplicated Plasmodium Falciparum Malaria

Trial Profile

A Phase 2 Interventional, Multicenter, Randomized Open Label Study to Determine the Effective and Tolerable Dose of KAF156 and Lumefantrine Solid Dispersion Formulation in Combination, Given Once Daily for 1, 2 and 3-days to Adults and Children With Uncomplicated Plasmodium Falciparum Malaria

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 29 Nov 2022

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At a glance

  • Drugs Ganaplacide (Primary) ; Lumefantrine (Primary) ; Artemether/lumefantrine
  • Indications Falciparum malaria
  • Focus Therapeutic Use
  • Sponsors Novartis; Novartis Healthcare; Novartis Pharma A.G.; Novartis Pharmaceuticals

Most Recent Events

  • 23 Nov 2022 According to a Novartis media release, this trial receive funding from the European and Developing Countries Clinical Trials Partnership (EDCTP), which is supported by the European Union.
  • 23 Nov 2022 Results presented in a Novartis Media Release.
  • 05 Oct 2021 According to a Novartis media release, results from this study will be published in the New England Journal of Medicine.

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