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Phase 1 trial of a selective orexin 1 receptor antagonist ACT-539313 in healthy male subjects: A first-in-human randomized, double-blind single-ascending dose study

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Phase 1 trial of a selective orexin 1 receptor antagonist ACT-539313 in healthy male subjects: A first-in-human randomized, double-blind single-ascending dose study

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 24 Feb 2020

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At a glance

  • Drugs Nivasorexant (Primary)
  • Indications Anxiety disorders
  • Focus Adverse reactions; First in man; Pharmacodynamics; Pharmacokinetics

    • Most Recent Events

    • 17 Feb 2020 Results published in the British Journal of Clinical Pharmacology
    • 24 Mar 2018 Status changed from recruiting to completed according to results presented at the 119th Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics.
    • 24 Mar 2018 Results presented at the 119th Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics

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