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A multi-national, multi-center, randomized Phase 2/3 study of Pazopanib plus Abexinostat versus Pazopanib monotherapy in patients with locally advanced or metastatic renal cell carcinoma (RCC)

Trial Profile

A multi-national, multi-center, randomized Phase 2/3 study of Pazopanib plus Abexinostat versus Pazopanib monotherapy in patients with locally advanced or metastatic renal cell carcinoma (RCC)

Status: Planning
Phase of Trial: Phase II/III

Latest Information Update: 31 May 2017

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At a glance

  • Drugs Abexinostat (Primary) ; Pazopanib (Primary)
  • Indications Renal cell carcinoma
  • Focus Registrational; Therapeutic Use
  • Acronyms PAX study
  • Most Recent Events

    • 31 May 2017 New trial record
    • 22 May 2017 According to a Xynomic Phatrmaceuicals media release, the company will work with regulatory agencies to plan this trial which could accelerate approval of Abexinostat for solid tumours.
    • 22 May 2017 According to a Xynomic Phatrmaceuicals media release, the company has entered into a strategic partnership with the University of California San Francisco (UCSF) to conduct this trial. This trial will be led by Pamela Munster and Rahul Aggarwal.
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