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A Multi-Centre Trial Evaluating Efficacy and Safety of Prophylactic Administration of Concizumab in Patients With Severe Haemophilia A Without Inhibitors

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Trial Profile

A Multi-Centre Trial Evaluating Efficacy and Safety of Prophylactic Administration of Concizumab in Patients With Severe Haemophilia A Without Inhibitors

Status: Suspended
Phase of Trial: Phase II

Latest Information Update: 04 Jan 2022

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At a glance

  • Drugs Concizumab (Primary) ; Turoctocog alfa
  • Indications Haemophilia A
  • Focus Therapeutic Use
  • Acronyms Explorer 5
  • Sponsors Novo Nordisk
  • Most Recent Events

    • 14 Dec 2021 Results (N=61) from phase 2 trials explorer4 (NCT03196284) and explorer5 (NCT03196297) describing surgeries and diagnostic procedures presented at the 63rd American Society of Hematology Annual Meeting and Exposition
    • 14 Dec 2021 Results of an exploratory pooled analyses (of explorer4 (NCT03196284) and explorer5 (NCT03196297) phase 2 trials) assessing changes in HRQoL after long-term concizumab treatment presented at the 63rd American Society of Hematology Annual Meeting and Exposition
    • 30 May 2021 This trial has been completed in Spain, according to European Clinical Trials Database record.

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