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A Phase II Open Label Single Arm Study of Adjuvant Nivolumab Following Chemo-Radiation in Localized Muscle-Invasive Bladder Cancer (NEXT)

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A Phase II Open Label Single Arm Study of Adjuvant Nivolumab Following Chemo-Radiation in Localized Muscle-Invasive Bladder Cancer (NEXT)

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 22 Mar 2024

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At a glance

  • Drugs Nivolumab (Primary)
  • Indications Adenocarcinoma; Bladder cancer; Squamous cell cancer; Ureteral neoplasms; Urethral cancer; Urogenital cancer
  • Focus Therapeutic Use
  • Acronyms NEXT

    • Most Recent Events

    • 18 Mar 2024 Planned End Date changed from 1 Sep 2027 to 31 Oct 2027.
    • 18 Mar 2024 Planned primary completion date changed from 1 Sep 2024 to 31 Oct 2024.
    • 27 Jan 2024 Results (n=28) assessing efficacy of adjuvant nivolumab to definitive CRT in pts with nmUC presented at the 2024 Genitourinary Cancers Symposium

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