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An Open-Label, Single-Arm, Multicenter Study to Evaluate the Effectiveness and Safety of Ixazomib (NINLARO) in Combination With Lenalidomide and Dexamethasone (IRD) in Patients With Multiple Myeloma Previously Receiving a Bortezomib-Based Induction Regimen (US MM-6)

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An Open-Label, Single-Arm, Multicenter Study to Evaluate the Effectiveness and Safety of Ixazomib (NINLARO) in Combination With Lenalidomide and Dexamethasone (IRD) in Patients With Multiple Myeloma Previously Receiving a Bortezomib-Based Induction Regimen (US MM-6)

Status: Active, no longer recruiting
Phase of Trial: Phase IV

Latest Information Update: 23 Sep 2024

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At a glance

  • Drugs Dexamethasone (Primary) ; Ixazomib (Primary) ; Lenalidomide (Primary)
  • Indications Multiple myeloma
  • Focus Therapeutic Use
  • Acronyms TOURMALINE MM-6; US MM-6
  • Sponsors Takeda Oncology

    • Most Recent Events

    • 15 Jun 2023 Results of sub-group analysis assessing clinical outcomes by age and frailty status, presented at the 28th Congress of the European Haematology Association.
    • 13 Dec 2022 Results of subgroup analysis in Patients Aged less than 75 and greater than 75 Years , presented at the 64th American Society of Hematology Annual Meeting and Exposition
    • 01 Oct 2022 Results from the fully accrued study cohort(US MM-6 Study) assessing Efficacy, Safety, and Quality of Life (QoL) in Patients With Newly Diagnosed Multiple Myeloma (NDMM) After In-Class Transition (iCT) From Parenteral Bortezomib-Based Induction Therapy to All-Oral Ixazomib-Lenalidomide-Dexamethasone (IRd) published in the Clinical Lymphoma, Myeloma & Leukemia

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