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Safety and Efficacy Evaluation of IM19 CAR-T Cells On CD19+ Refractory or Relapsed B-ALL Patients

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Trial Profile

Safety and Efficacy Evaluation of IM19 CAR-T Cells On CD19+ Refractory or Relapsed B-ALL Patients

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 17 Jan 2023

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At a glance

  • Drugs IM19 chimeric antigen receptor T cell therapy Beijing Immunochina Medical Science and Technology (Primary) ; Cyclophosphamide; Fludarabine
  • Indications B-cell leukaemia; Precursor B-cell lymphoblastic leukaemia-lymphoma; Precursor cell lymphoblastic leukaemia-lymphoma
  • Focus Adverse reactions
  • Sponsors Beijing Immunochina Medical Science and Technology
  • Most Recent Events

    • 13 Dec 2022 Results assessing benefits of a second Allo-HSCT after CAR-T Cell therapy presented at the 64th American Society of Hematology Annual Meeting and Exposition
    • 01 Mar 2022 Results from rom 5 clinical trials (NCT03173417, NCT02546739, NCT03671460, ChiCTR-ONC-17012829, and ChiCTR1800016541) assessing Factors associated with treatment response to CD19 CAR-T therapy among a large cohort of B cell acute lymphoblastic leukemia published in the Cancer Immunology Immunotherapy
    • 01 Feb 2022 Results of a retrospective analysis assessing Cytoplasmic CD79a as a promising biomarker for B lymphoblastic leukemia follow up post CD19 CAR-T therapy published in the Leukemia and Lymphoma
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