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A Phase I, Open Label, Dose Escalation/Expansion Study to Evaluate the Safety, Tolerability and Pharmacokinetics of SHR7390 Combined With SHR-1210 and SHR3162 in Patients With Advanced Solid Tumors

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Trial Profile

A Phase I, Open Label, Dose Escalation/Expansion Study to Evaluate the Safety, Tolerability and Pharmacokinetics of SHR7390 Combined With SHR-1210 and SHR3162 in Patients With Advanced Solid Tumors

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 30 Jan 2023

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At a glance

  • Drugs Camrelizumab (Primary) ; Fuzuloparib (Primary) ; SHR 7390 (Primary)
  • Indications Colorectal cancer; Solid tumours
  • Focus Adverse reactions
  • Sponsors Jiangsu Hengrui Medicine Co.

    • Most Recent Events

    • 18 Jan 2023 Results assessing tolerability, safety and antitumor activity of SHR7390 monotherapy for advanced solid tumors and SHR7390 plus camrelizumab for treatment-refractory advanced or metastatic colorectal cancer in two studies (NCT02968485 and NCT03182673) published in the Oncologist.
    • 30 Aug 2022 Status changed from recruiting to discontinued.
    • 08 Jun 2021 Results presented at the 57th Annual Meeting of the American Society of Clinical Oncology

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