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A Randomized Phase 2 Study of the Safety, Efficacy, and Immune Response of CRS-207, Nivolumab, and Ipilimumab With or Without GVAX Pancreas Vaccine (With Cyclophosphamide) in Patients With Previously Treated Metastatic Pancreatic Adenocarcinoma

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Trial Profile

A Randomized Phase 2 Study of the Safety, Efficacy, and Immune Response of CRS-207, Nivolumab, and Ipilimumab With or Without GVAX Pancreas Vaccine (With Cyclophosphamide) in Patients With Previously Treated Metastatic Pancreatic Adenocarcinoma

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 09 Apr 2019

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At a glance

  • Drugs CRS 207 (Primary) ; Ipilimumab (Primary) ; Nivolumab (Primary) ; Tumour cell vaccine-GVAX (Primary) ; Cyclophosphamide
  • Indications Adenocarcinoma; Pancreatic cancer
  • Focus Therapeutic Use

    • Most Recent Events

    • 04 Apr 2019 Planned End Date changed from 1 Oct 2019 to 1 Oct 2023.
    • 04 Apr 2019 Planned primary completion date changed from 1 Oct 2019 to 1 Oct 2023.
    • 31 Aug 2018 Biomarkers information updated
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