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A pilot study to test the feasibility, safety and efficacy of the addition of the BiTE antibody Blinatumomab to the Interfant-06 backbone in infants with MLL-rearranged acute lymphoblastic leukemia. A collaborative study of the Interfant network

Trial Profile

A pilot study to test the feasibility, safety and efficacy of the addition of the BiTE antibody Blinatumomab to the Interfant-06 backbone in infants with MLL-rearranged acute lymphoblastic leukemia. A collaborative study of the Interfant network

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 28 Apr 2023

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At a glance

  • Drugs Blinatumomab (Primary)
  • Indications Precursor B-cell lymphoblastic leukaemia-lymphoma
  • Focus Adverse reactions
  • Acronyms Blinatumomab in infant ALL
  • Most Recent Events

    • 27 Apr 2023 Results assessing safety and efficacy of blinatumomab, a bispecific T-cell engager molecule targeting CD19, in infants with KMT2A-rearranged ALL published in the New England Journal of Medicine
    • 14 Dec 2021 Results presented at the 63rd American Society of Hematology Annual Meeting and Exposition
    • 29 Oct 2021 Planned End Date changed from 17 Oct 2022 to 31 Jan 2024.
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