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A Phase I, Multicenter Dose-Escalation Study to Assess the Tolerability, Pharmacokinetics and Preliminary Anti-tumor Activity of AZD5153 in Patients With Relapsed/Refractory Malignant Solid Tumors, Including Lymphomas

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A Phase I, Multicenter Dose-Escalation Study to Assess the Tolerability, Pharmacokinetics and Preliminary Anti-tumor Activity of AZD5153 in Patients With Relapsed/Refractory Malignant Solid Tumors, Including Lymphomas

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 05 Nov 2021

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At a glance

  • Drugs SRA 515 (Primary) ; Olaparib
  • Indications Adenocarcinoma; Carcinoma; Fallopian tube cancer; Lymphoma; Ovarian cancer; Pancreatic cancer; Peritoneal cancer; Prostate cancer; Solid tumours; Triple negative breast cancer
  • Focus Adverse reactions; First in man
  • Sponsors AstraZeneca

    • Most Recent Events

    • 05 May 2021 Status changed from active, no longer recruiting to completed.
    • 20 Oct 2020 Status changed from recruiting to active, no longer recruiting.
    • 04 Sep 2020 Planned number of patients changed from 72 to 100.

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