Trial Profile

NCI-COG Pediatric MATCH (Molecular Analysis for Therapy Choice)- Phase 2 Subprotocol of Ensartinib in Patients With Tumors Harboring ALK or ROS1 Genomic Alterations

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 09 Oct 2025

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At a glance

Drugs Ensartinib (Primary)
Indications CNS cancer; Ependymoma; Ewing's sarcoma; Glioma; Hepatoblastoma; Langerhans cell histiocytosis; Medulloblastoma; Neuroblastoma; Non-Hodgkin's lymphoma; Osteosarcoma; Rhabdomyosarcoma; Soft tissue sarcoma; Solid tumours; Wilms' tumour
Focus Therapeutic Use
Acronyms Pediatric MATCH

Most Recent Events

07 Oct 2025 Planned End Date changed from 31 Oct 2025 to 3 Oct 2026.
17 Sep 2025 Planned End Date changed from 30 Sep 2025 to 31 Oct 2025.
17 Sep 2025 Planned primary completion date changed from 30 Sep 2025 to 31 Oct 2025.

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