Trial Profile

A Phase 2 Open-Label Study Evaluating Tolerability and Efficacy of Navitoclax Alone or in Combination With Ruxolitinib in Subjects With Myelofibrosis (REFINE)

Status: Completed

Phase of Trial: Phase II

Latest Information Update: 14 Mar 2025

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At a glance

12 Mar 2025 Status changed from active, no longer recruiting to completed.
27 Jun 2024 Planned End Date changed from 2 Feb 2029 to 29 Jan 2025.
13 Dec 2022 Results(As of Feb 07, 2022: N = 32 of Cohort-3) investigating whether the type of Myelofibrosis correlated with clinical outcomes and responses suggestive of disease modification among JAKi treatment naive patients and risk presented at the 64th American Society of Hematology Annual Meeting and Exposition

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