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An Open-label, Phase 1B Study of NEO-PV-01 + CD40 Agonist Antibody (APX005M) or Ipilimumab With Nivolumab in Patients With Advanced or Metastatic Melanoma

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Trial Profile

An Open-label, Phase 1B Study of NEO-PV-01 + CD40 Agonist Antibody (APX005M) or Ipilimumab With Nivolumab in Patients With Advanced or Metastatic Melanoma

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 17 May 2023

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At a glance

  • Drugs Ipilimumab (Primary) ; NEO-PV 01 (Primary) ; Nivolumab (Primary) ; Poly ICLC (Primary) ; Sotigalimab (Primary)
  • Indications Malignant melanoma
  • Focus Adverse reactions
  • Sponsors BioNTech; Neon Therapeutics

    • Most Recent Events

    • 01 Sep 2020 Status changed from active, no longer recruiting to discontinued.
    • 27 Nov 2019 Status changed from recruiting to active, no longer recruiting.
    • 20 Nov 2019 According to a Neon Therapeutics media release, the company plans to cease future enrollment in its NT-003 trial in metastatic melanoma.

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