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Multicenter Phase II study to evaluate efficacy and safety of combination therapy with trastuzumab and pertuzumab in patients with HER2-positive metastatic colorectal cancer

Trial Profile

Multicenter Phase II study to evaluate efficacy and safety of combination therapy with trastuzumab and pertuzumab in patients with HER2-positive metastatic colorectal cancer

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 03 Jul 2024

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At a glance

  • Drugs Pertuzumab (Primary) ; Trastuzumab (Primary)
  • Indications Adenocarcinoma; Colorectal cancer
  • Focus Therapeutic Use
  • Acronyms TRIUMPH

Most Recent Events

  • 04 Jun 2024 Results of the dynamic changes in both the tumor and its microenvironment in response to treatment and mechanisms of acquired resistance using spatial transcriptomics, presented at the 60th Annual Meeting of the American Society of Clinical Oncology
  • 13 Sep 2022 Results assessing diagnostic accuracy of Gene-Protein Assay to find HER2 intratumoral genetic and non-genetic heterogeneity using samples from this trial presented at the 47th European Society for Medical Oncology Congress
  • 27 Jun 2022 Planned End Date changed from 31 Mar 2023 to 30 Apr 2022.

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