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QUILT-3.055: A Phase IIb, Multicohort, Open-Label Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With PD-1/PD-L1 Immune Checkpoint Inhibitors

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Trial Profile

QUILT-3.055: A Phase IIb, Multicohort, Open-Label Study of Combination Immunotherapies in Patients Who Have Previously Received Treatment With PD-1/PD-L1 Immune Checkpoint Inhibitors

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 24 Oct 2025

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At a glance

  • Drugs Atezolizumab (Primary) ; Avelumab (Primary) ; Durvalumab (Primary) ; Nivolumab (Primary) ; Nogapendekin alfa inbakicept (Primary) ; PD-L1-t-haNK (Primary) ; Pembrolizumab (Primary)
  • Indications Adenocarcinoma; Cervical cancer; Colorectal cancer; Gastric cancer; Head and neck cancer; Liver cancer; Malignant melanoma; Merkel cell carcinoma; Non-small cell lung cancer; Oesophageal cancer; Renal cell carcinoma; Small cell lung cancer; Solid tumours; Squamous cell cancer; Urogenital cancer
  • Focus Therapeutic Use
  • Acronyms QUILT-3.055
  • Sponsors Altor BioScience Corporation; ImmunityBio

Most Recent Events

  • 20 Oct 2025 "Prolongation of Overall Survival (OS) with NAI Therapy by ALC Response" added as one more primary end-point.
  • 19 Sep 2025 Status changed from recruiting to active, no longer recruiting.
  • 08 Sep 2025 According to an ImmunityBio media release, results from this were presented (P1.11.78) on Sunday, September 7, at the IASLC 2025 World Conference on Lung Cancer in Barcelona, Spain.

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