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A Phase 2, Open-Label, Single Arm Study to Evaluate the Safety and Efficacy of Pembrolizumab in Participants with Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma (R/M cSCC)

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Trial Profile

A Phase 2, Open-Label, Single Arm Study to Evaluate the Safety and Efficacy of Pembrolizumab in Participants with Recurrent or Metastatic Cutaneous Squamous Cell Carcinoma (R/M cSCC)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 18 Sep 2024

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At a glance

  • Drugs Pembrolizumab (Primary)
  • Indications Skin cancer; Squamous cell cancer
  • Focus Registrational; Therapeutic Use
  • Acronyms KEYNOTE-629; MK-3475-629/KEYNOTE-629
  • Sponsors Merck Sharp & Dohme Corp.
  • Most Recent Events

    • 18 Sep 2024 This trial has been completed in Spain (Global end date: 2023-09-13) according to European Clinical Trials Database record.
    • 04 Jun 2024 Results (additional follow-up of 38 months) assessing safety and efficacy of Pembrolizumab for locally advanced or recurrent/metastatic cutaneous squamous cell carcinoma presented at the 60th Annual Meeting of the American Society of Clinical Oncology
    • 15 May 2024 According to a Merck & Co media release, data from this trial will be presented will be presented at the 2024 American Society of Clinical Oncology (ASCO) Annual Meeting in Chicago from May 31-June.

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