Trial Profile
A Single-Center, Phase I, Randomized, Double Blind, Placebo-Controlled, First-In-Human Trial to Assess the Safety, Tolerability, Immunogenicity, Pharmacokinetics, and Pharmacodynamics of Single Ascending Doses of Subcutaneous Injected M6495 (Anti-ADAMTS-5 Nanobody) in Healthy Male Subjects
Status:
Completed
Phase of Trial:
Phase I
Latest Information Update: 17 Sep 2021
Price :
$35
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At a glance
- Drugs M 6495 (Primary)
- Indications Osteoarthritis
- Focus Adverse reactions; First in man
- Sponsors Merck KGaA
- 07 Sep 2018 Status changed from active, no longer recruiting to completed.
- 19 Jul 2018 Status changed from recruiting to active, no longer recruiting.
- 12 Apr 2018 Planned number of patients changed from 45 to 54.