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A Phase II Trial of PET-Directed Therapy Using AVD (Doxorubicin, Vinblastine, and Dacarbazine) Plus Brentuximab Vedotin Induction Chemotherapy, With or Without Brentuximab Vedotin Plus Nivolumab, Followed by Nivolumab Consolidation for Patients With Previously Untreated Non-Bulky Limited Stage Hodgkin Lymphoma

Trial Profile

A Phase II Trial of PET-Directed Therapy Using AVD (Doxorubicin, Vinblastine, and Dacarbazine) Plus Brentuximab Vedotin Induction Chemotherapy, With or Without Brentuximab Vedotin Plus Nivolumab, Followed by Nivolumab Consolidation for Patients With Previously Untreated Non-Bulky Limited Stage Hodgkin Lymphoma

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 19 Sep 2023

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At a glance

  • Drugs Nivolumab (Primary) ; Brentuximab vedotin; Dacarbazine; Doxorubicin; Vinblastine
  • Indications Hodgkin's disease
  • Focus Therapeutic Use
  • Most Recent Events

    • 14 Sep 2023 Planned End Date changed from 7 Aug 2024 to 8 Jul 2025.
    • 15 Aug 2023 Planned primary completion date changed from 1 Aug 2023 to 1 Aug 2024.
    • 13 Dec 2022 Results reporting efficacy and safety data with a median follow-up of 22 months presented at the 64th American Society of Hematology Annual Meeting and Exposition
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