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An Open Label, Randomised, Pre-surgical, Pharmacodynamics Study to Compare the Biological Effects of AZD9496 Versus Fulvestrant in Postmenopausal Women With ER Positive HER-2 Negative Primary Breast Cancer

Trial Profile

An Open Label, Randomised, Pre-surgical, Pharmacodynamics Study to Compare the Biological Effects of AZD9496 Versus Fulvestrant in Postmenopausal Women With ER Positive HER-2 Negative Primary Breast Cancer

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 05 Nov 2021

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At a glance

  • Drugs AZD 9496 (Primary) ; Fulvestrant
  • Indications Early breast cancer
  • Focus Pharmacodynamics
  • Sponsors AstraZeneca

Most Recent Events

  • 31 Mar 2020 Primary endpoint (Pharmacodynamics changes to estrogen receptor (ER) expression following treatment with AZD9496 or fulvestrant) has not been met.
  • 31 Mar 2020 Results published in the Clinical Cancer Research
  • 04 Mar 2019 Status changed from active, no longer recruiting to completed.

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