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Window of Opportunity Trial of Nivolumab and Tadalafil in Patients With Squamous Cell Carcinoma of the Head and Neck

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Trial Profile

Window of Opportunity Trial of Nivolumab and Tadalafil in Patients With Squamous Cell Carcinoma of the Head and Neck

Status: Completed
Phase of Trial: Phase 0

Latest Information Update: 06 Oct 2022

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At a glance

  • Drugs Nivolumab (Primary) ; Tadalafil (Primary)
  • Indications Head and neck cancer; Hypopharyngeal cancer; Laryngeal cancer; Mouth neoplasm; Oropharyngeal cancer; Squamous cell cancer
  • Focus Pharmacodynamics
  • Most Recent Events

    • 04 Oct 2022 Status changed from active, no longer recruiting to completed.
    • 13 Sep 2022 Results from NCT03238365, NCT03854032 assessing the frequency of discordant pathologic tumor response in HNSCC patients treated with ICI , presented at the 47th European Society for Medical Oncology Congress
    • 15 Aug 2022 Planned End Date changed from 16 Jul 2021 to 1 Nov 2022.

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