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A Phase 1 Study Evaluating the Safety, Pharmacokinetics, and Anti-tumor Activity of ABBV-321 in Subjects With Advanced Solid Tumors Associated With Overexpression of the Epidermal Growth Factor Receptor (EGFR)

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Trial Profile

A Phase 1 Study Evaluating the Safety, Pharmacokinetics, and Anti-tumor Activity of ABBV-321 in Subjects With Advanced Solid Tumors Associated With Overexpression of the Epidermal Growth Factor Receptor (EGFR)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 21 Apr 2022

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At a glance

  • Drugs Serclutamab talirine (Primary)
  • Indications Bladder cancer; Cervical cancer; Colorectal cancer; Glioblastoma; Head and neck cancer; Non-small cell lung cancer; Oesophageal cancer; Renal cancer; Sarcoma; Solid tumours; Squamous cell cancer
  • Focus Adverse reactions; First in man; Pharmacokinetics
  • Sponsors AbbVie
  • Most Recent Events

    • 18 Mar 2022 Results assessing pharmacokinetics and Exposure-response Analysis of Abbv-321 presented at the 123rd Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics
    • 05 May 2021 Status changed from active, no longer recruiting to completed.
    • 10 Feb 2021 Status changed from recruiting to active, no longer recruiting.

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