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Phase III Randomized Adjuvant Study of Pembrolizumab in muScle invaSive and locAlly aDvanced urOthelial caRcinoma (AMBASSADOR) Versus Observation

Trial Profile

Phase III Randomized Adjuvant Study of Pembrolizumab in muScle invaSive and locAlly aDvanced urOthelial caRcinoma (AMBASSADOR) Versus Observation

Status: Active, no longer recruiting
Phase of Trial: Phase III

Latest Information Update: 08 Apr 2024

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At a glance

  • Drugs Pembrolizumab (Primary)
  • Indications Bladder cancer; Carcinoma; Urethral cancer; Urogenital cancer
  • Focus Therapeutic Use
  • Acronyms AMBASSADOR; KEYNOTE-123
  • Most Recent Events

    • 27 Jan 2024 Results (n=702; Between 09/2017 and 08/2021) assessing the efficacy and safety of pembrolizumab in muscle-invasive and locally advanced urothelial carcinoma, presented at the 2024 Genitourinary Cancers Symposium.
    • 26 Jan 2024 According to a Merck & Co media release,trials other dual primary endpoint of overall survival did not reach statistical significance at the time of this interim analysis and will continue to be followed as data mature
    • 26 Jan 2024 According to a Merck & Co media release, result will be published in oral abstract session at the 2024 American Society of Clinical Oncology (ASCO) Genitourinary (GU) Cancers Symposium (abstract #LBA531).
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