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A Phase II/III, Open-label Clinical Trial to Study the Efficacy and Safety of the Combination Regimen of MK-3682B (MK-3682 + Grazoprevir + MK-8408 Fixed Dose Combination) in Subjects with Chronic Hepatitis C Virus GT5 or GT6 Infection

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Trial Profile

A Phase II/III, Open-label Clinical Trial to Study the Efficacy and Safety of the Combination Regimen of MK-3682B (MK-3682 + Grazoprevir + MK-8408 Fixed Dose Combination) in Subjects with Chronic Hepatitis C Virus GT5 or GT6 Infection

Status: Discontinued
Phase of Trial: Phase II/III

Latest Information Update: 01 Aug 2022

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At a glance

  • Drugs Grazoprevir/ruzasvir/uprifosbuvir (Primary)
  • Indications Hepatitis C
  • Focus Registrational; Therapeutic Use
  • Sponsors Merck Sharp & Dohme

    • Most Recent Events

    • 29 Sep 2017 According to a Merck AG media release, based on a review of Phase 2 efficacy data, the company has discontinued the development of the investigational combination regimens MK-3682B (grazoprevir/ruzasvir/ uprifosbuvir).
    • 29 Sep 2017 Status changed from recruiting to discontinued, as reported in a Merck AG media release.
    • 14 Aug 2017 New trial record

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