Multi-center Phase I/II Study of NY-ESO-1 T Cell Receptor Gene Transferred T Lymphocytes in Patients with Synovial Sarcoma
Latest Information Update: 25 Nov 2024
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At a glance
- Drugs Mipetresgene autoleucel (Primary) ; Cyclophosphamide
- Indications Synovial sarcoma
- Focus Adverse reactions; Pharmacokinetics; Therapeutic Use
- Sponsors Takara Bio
- 05 Dec 2023 Status changed from active, no longer recruiting to completed.
- 06 Jun 2023 Results assessing safety and the efficacy of gene engineered autologous T cell product with NY-ESO-1 siTCR retroviral vector which expressed affinity-enhanced NY-ESO-1-specific TCR and siRNA to silence endogenous TCR, presented at the 59th Annual Meeting of the American Society of Clinical Oncology.
- 06 Oct 2020 Planned End Date changed from 31 Jan 2034 to 1 Jan 2034.